Eric Dane, best known for his role as Dr. Mark “McSteamy” Sloan on Grey’s Anatomy, has passed away at the age of 53. His family confirmed he died on Thursday, February 19, 2026, after a courageous and very public battle with amyotrophic lateral sclerosis (ALS) — also known as Lou Gehrig’s disease.
His family released a statement saying he spent his final days surrounded by loved ones, including his wife and their two daughters. They asked for privacy during their grief.
His Most Beloved Roles
Eric Dane had a long and varied acting career, but he became a household name for:
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Dr. Mark Sloan (“McSteamy”) on Grey’s Anatomy — the charismatic plastic surgeon whose charm and chemistry with other characters made him unforgettable.
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Cal Jacobs on Euphoria — a complex, intense role in the hit HBO drama that brought him acclaim in a very different kind of TV series.
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He also appeared in films including “Marley & Me”, “X-Men: The Last Stand”, “Burlesque”, and “Valentine’s Day”, and had early TV roles in shows like The Wonder Years and Charmed.
His portrayal of Mark Sloan, the confident surgeon affectionately nicknamed McSteamy, was one of the most iconic characters in Grey’s Anatomy history and helped cement his place in pop-culture memory.
Battle with ALS
Eric Dane first revealed his diagnosis of amyotrophic lateral sclerosis in April 2025, a progressive and incurable neurological disease that affects nerve cells in the brain and spinal cord. There is currently no cure, and ALS gradually robs patients of muscle control, speech, and the ability to swallow or breathe independently.
Despite his illness, Dane continued to work when he could, even filming scenes for Euphoria in a wheelchair before his health declined. He became a passionate advocate for ALS awareness and research, using his platform to speak publicly about the disease and the urgent need for more support.
In late 2025, he received recognition for his advocacy efforts, including public appearances focused on increasing understanding of ALS.
Legacy
Eric Dane’s death has prompted outpourings of grief and tributes from friends, co-stars, and fans around the world who remember him both for his iconic screen roles and his bravery in facing such a devastating illness.
He leaves behind a legacy of memorable performances, heartfelt advocacy, and the impact of a life lived with courage in the public eye.