ABC has officially announced the return of its hit medical drama. Grey’s Anatomy Season 22 will premiere this fall. Fans are eager for new episodes after a dramatic season finale.
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The new season will continue the story from the shocking explosion. It will also introduce a new character to the hospital.
Grey’s Anatomy Season 22 Premiere Date and Time
Grey’s Anatomy Season 22 will debut on Thursday, October 9, 2025. It will air at 10:00 p.m. ET/PT on the ABC network. This is a new timeslot for the long-running series.
Episodes will be available for streaming the next day on Hulu. This allows viewers to watch at their convenience.
Grey’s Anatomy Season 22 Cast and New Additions
Most series regulars are confirmed to return. Ellen Pompeo will reprise her role as Meredith Grey. Her involvement will be more substantial than in recent seasons.
According to ABC, Chandra Wilson and James Pickens Jr. are returning. Kim Raver, Kevin McKidd, and Caterina Scorsone are also back. Chris Carmack’s status as Link remains a central mystery.
New Face Joins Grey Sloan Memorial
Actor Luke Tennie is joining the cast in Season 22. He will play a new character named Dominic. Dominic is a teacher at the hospital’s training program.
His arrival will likely create new dynamics among the staff. Tennie is known for his role in the Apple TV+ series Shrinking.
Plot Expectations After the Season 21 Finale
The Season 21 finale ended with a massive explosion. A desperate mother triggered a bomb inside the hospital. Several main characters were caught in the blast zone.
The immediate aftermath will dominate the early episodes. Link’s fate is a primary concern for fans and other characters.
Focus on Relationships and Character Arcs
The new season will also explore ongoing personal stories. Simone Griffith and Lucas Adams reconciled their relationship. Their romance will continue to develop.
Tension between Jules Millin and Winston Ndugu will be addressed. The professional and personal fallout will be a key storyline.
Trusted Sources
ABC, Variety, The Hollywood Reporter, Deadline, Hulu.
Info at your fingertips
When does Grey’s Anatomy Season 22 start?
The season premiere is on October 9, 2025. It will air at 10:00 p.m. ET/PT on ABC.
Where can I watch the new season online?
New episodes stream on Hulu the day after they air on ABC. A Hulu subscription is required for access.
Is Ellen Pompeo leaving Grey’s Anatomy?
No, Ellen Pompeo is returning for Season 22. She will have a larger presence compared to recent seasons.
Did Link survive the explosion?
His fate was left unclear in the finale. The character’s status will be a major plot point early in the new season.
Who is the new actor joining the cast?
Luke Tennie is joining the show as a new character named Dominic. He will be a teacher at the hospital.
How many episodes will Season 22 have?
The season is expected to have a standard episode count. This will likely be around 18 to 20 episodes in total.
