Grey’s Anatomy Season 22 Episode 4: What to Expect in “Goodbye Horses” md06

Jackson Avery returns, but with bad news for Meredith, on Grey’s Anatomy Season 22 Episode 4, “Goodbye Horses.”

While Meredith has been spending her time at Grey-Sloan, things have apparently been moving forward elsewhere. She finds out that Jackson let Tom Koracick publish his Alzheimer’s results, despite the fact that his research had only been on male mice.

Meanwhile, Link is discharged from the hospital, and the relationship between Teddy and Cass Beckman makes for an awkward encounter with Owen.

Grey’s Anatomy Season 22 Episode 4 – “Goodbye Horses” – (Disney/Anne Marie Fox) SOPHIA BUSH

Here’s everything you need to know about this episode, including the air date, cast, promo, and how to watch.

Grey’s Anatomy Season 22 Episode 4 Details

• Title: “Goodbye Horses”
• Air Date: Thursday, October 30th, 2025
• Time: 10/9c
• Network: ABC

How to Watch Grey’s Anatomy Season 22 Episode 4

• Live: ABC at 10/9c
• Streaming: Available next day on Hulu

Grey’s Anatomy Season 22 Episode 4 Description

The interns juggle a bizarre trauma, while a complex breast reconstruction forces Meredith into a tense partnership.

Guest Stars & Returning Characters

• Cast: Chandra Wilson, Kevin McKidd, Kim Raver, James Pickens Jr., Chris Carmack, Camilla Luddington, Anthony Hill, Jason George, Alexis Floyd, Adelaide Kaine, Harry Shum Jr., Nico Terho, Trevor Jackson, Ellen Pompeo
• Guest Stars: Jesse Williams, Sophia Bush, Floriana Lima, Samantha Marie Ware, Raphael Alejandro, Manny Magnus, Anton Starkman
• Notable Returns: Jesse Williams as Jackson Avery, Sophia Bush as Cass Beckman, Floriana Lima as Nora Young

More Photos from Grey’s Anatomy Season 22 Episode 4:

Grey’s Anatomy Season 22 Episode 4 – “Goodbye Horses” – (Disney/Anne Marie Fox) RAPHAEL ALEJANDRO

Grey’s Anatomy Season 22 Episode 4 – “Goodbye Horses” – (Disney/Anne Marie Fox) FLORIANA LIMA