Kaley Cuoco continues to prove that life after The Big Bang Theory has only strengthened her career momentum. Her upcoming MGM+ mystery thriller Vanished, premiering in February 2026, extends an impressive post-sitcom streak that has seen the actress successfully reinvent herself.
Since the long-running CBS comedy ended in 2019, Cuoco has deliberately stepped away from traditional sitcom roles, carving out a niche in darker, suspense-driven stories. After earning critical acclaim for The Flight Attendant and Based on a True Story, Vanished places her back at the center of a high-stakes mystery. The series follows Cuoco as a woman whose romantic European getaway spirals into danger when her partner, played by Sam Claflin, disappears.
Once best known as Penny, the grounded heart of The Big Bang Theory, Cuoco has embraced morally complex, emotionally intense roles that showcase her range. With Vanished, she reinforces that mystery thrillers — not sitcoms — now define the most compelling chapter of her career.