
Grey Sloan Memorial Hospital and its staff are on the long path to recovery after a major explosion in the season premiere left multiple people injured, one character dead and caused severe damage to the structure.
The blast, caused by a cauterization tool igniting gas in an operating room, injured multiple characters, including Dr. Atticus Lincoln (Chris Carmack). Known as the goofball Link on the show, the orthopedic surgeon was the most severely injured character and shared an emotional farewell phone call with his new wife, Dr. Jo Wilson (Camilla Luddington), though he miraculously survived.
Showrunner Meg Marinis told TV Insider the new season “will touch on the long road to recovery.”
In the upcoming episode, which is also the show’s 450th, “the team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations,” according to ABC, while Meredith spends time with Amelia.
Here’s what to know about the next episode of “Grey’s Anatomy” Season 22, including release date, time and cast.
When does the next episode of ‘Grey’s Anatomy’ Season 22 come out?
The next episode of “Grey’s Anatomy” Season 22, which is also the show’s 450th episode, will air on ABC on Thursday, Oct. 16 at 10 p.m. ET/ 9 p.m. CT. The episode, titled “We Built This City,” will be available to stream on Hulu the next day.
Watch ‘Grey’s Anatomy’ on Hulu
‘Grey’s Anatomy’ Season 22 episode schedule
New “Grey’s Anatomy” Season 22 episodes drop weekly on Thursdays on ABC starting Oct. 9, with them becoming available to stream on Hulu the following day.
However, the series will go on hiatus in November and return midseason sometime in 2026. ABC has not specified the date the series will return from the break.
Seasons 1 to 21 of “Grey’s Anatomy” are available to stream on Hulu and Netflix.
‘Grey’s Anatomy’: Stream on Hulu
How many episodes will ‘Grey’s Anatomy’ Season 22 have?
Season 22 of “Grey’s Anatomy” will have 18 episodes, an ABC spokesperson confirmed to USA TODAY. The season will also include a big milestone: the second episode of the season, “We Built This City,” will be the show’s 450th episode.
New episodes will drop weekly on Thursdays.
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‘Grey’s Anatomy’ Season 22 cast
Cast members for Season 22 of “Grey’s Anatomy” include:
- Ellen Pompeo as Dr. Meredith Grey
- Chandra Wilson as Miranda Bailey
- James Pickens Jr. as Richard Webber
- Kevin McKidd as Owen Hunt
- Kim Raver as Teddy Altman
- Camilla Luddington as Jo Wilson
- Caterina Scorsone as Amelia Shepherd
- Jason George as Ben Warren
- Chris Carmack as Atticus “Link” Lincoln
- Scott Speedman as Nick Marsh
- Anthony Hill as Winston Ndugu
- Niko Terho as Lucas Adams
- Alexis Floyd as Simone Griffith
- Harry Shum Jr. as Benson Kwan
- Adelaide Kane as Jules Millin
Watch the ‘The Grey’s Anatomy’ Season 22 trailer
ABC dropped the trailer for Season 22 of “Grey’s Anatomy” on Sept. 30.
Will ‘Grey’s Anatomy’ return for Season 23?
ABC has not made any announcements regarding Season 23 of “Grey’s Anatomy” yet.