
Grey’s Anatomy season 21, episode 18 did that with the episode’s biggest moments, especially in relation to Simone and Lucas’s relationship, where their being in danger reminded them of their wish to be together, and Owen and Teddy’s marriage, whose personal journeys led them to opposite realizations. It also set up some storylines only briefly tackled in season 21 that can be central in season 22. Finally, Grey’s Anatomy season 21’s very ending introduced a major twist that will heavily impact season 22 with the explosion in the episode’s final moments, making it imperative for some questions to be answered.
8Is Link Alive?
Grey’s Anatomy Season 21’s Last Moment Implied His Actions Caused The Explosion
One of the biggest questions Grey’s Anatomy season 21’s ending generated was about the safety of Atticus Lincoln. After spending the entirety of Grey’s Anatomy season 21, episode 18 secluded with Jo in a supply closet as their reimagination of a honeymoon after all their surgeries and patient appointments were delayed, the solving of the hostage situation brought Link back to his original patient schedule.

Jo and Link’s day before their wedding hilariously exemplified the strengths of their relationship in Grey’s Anatomy season 21, episode 17.
7How Has The Explosion Affected Bailey, Beltran & Millin?
The 3 Doctors Could All Be Seen On The OR Floor
While potentially less in danger of perishing in the explosion than Link, other doctors were shown close to the OR where the hostage situation had developed mere hours before. Its resolution, along with the arrest of Jenna Gatlin, made everyone feel automatically safer and ready to restart the day’s surgeries, but Grey’s Anatomy season 21, episode 18’s last moment quickly proved everybody wrong with the unexpected explosion.
Jenna Gatlin’s actions took everyone by surprise in the Grey’s Anatomy season 21 finale, but her exasperation could already be perceived in the previous episode, after Amelia, Monica, Lucas and Simone all recommended waiting as the best path to follow in Dylan’s situation.
6Does Meredith Returning To Use Catherine’s Labs Open Up To A Fox Foundation Collaboration?
Meredith Will Use Catherine’s Spaces In Boston & Operate At Grey Sloan Memorial
Grey’s Anatomy season 21’s premiere established that Meredith discovering Catherine’s worsening symptoms and treating her helped her detach her Alzheimer’s research from the Fox Foundation, effectively making it easier for her and Amelia to study Alzheimer’s without them blocking their every move. Grey’s Anatomy season 21 also set up Meredith and Amelia’s Alzheimer’s research’s next steps through Meredith’s decision to fund the research herself. However, Meredith and Catherine’s new plan put them in each other’s orbit again.
A major unexplored story was Jackson’s wish to be part of the research in Grey’s Anatomy season 21, something season 22 makes more likely through Meredith and Catherine’s new deal.
5What’s The Status Of Ndugu’s Mentorship Of Millin After His Confession?
Millin Vehemently Disagreed With Ndugu’s Perception Of What Happened
Winston Ndugu’s mentorship of Jules Millin brought them to spend much time together on cardiothoracic surgery cases, and the insistence with which Winston categorically denied falling for Jules hinted at Grey’s Anatomy season 21 setting them up as a new couple. Winston’s refusal to let Jules spend time on his service nonetheless alerted her to the problem, finally leading her to confront Winston in Grey’s Anatomy season 21, episode 18.
Winston’s admission of feeling lines were getting blurred by their spending so much time together enraged Jules, as not only she hadn’t perceived that, but she also felt she was being punished for something that had nothing to do with her. Jules going to ask Beltran to assist on her surgery heavily hinted at her mentorship with Ndugu potentially ending, making it imperative for Grey’s Anatomy season 22 to continue exploring that story and dynamic as a result.
4Did Simone Tell Lucas About The Intern?
Simone’s One Night Stand Is Part Of The Incoming Class Of Interns
Simone’s reaction to Lucas ending things with her right before Jo and Link’s wedding in Grey’s Anatomy season 21, episode 17 included going to Joe’s and impulsively sleeping with a stranger, something she seemingly regretted doing in Grey’s Anatomy season 21’s finale. However, what made everything more difficult was Grey’s Anatomy season 21, episode 18’s reveal that Simone’s one-night stand was none other than a new Grey Sloan Memorial intern.
3What’s Ben’s Residency Status After Teddy’s Decision?
Grey’s Anatomy Season 21’s Finale Didn’t Show Ben Getting Sacked
At the beginning of Grey’s Anatomy season 21, episode 18, Bailey wanted her husband to learn that Teddy wouldn’t recommend the board to bring him in permanently as a resident from her. The episode saw Ben and Miranda both operate on a patient in the ER who would have died had they not taken care of him, even if doing so in the ER didn’t follow protocol.

Ben’s return to Grey Sloan finally reunited him with his fellow resident Jo Wilson, thus highlighting an unexpectedly sad truth about interns.
While the decision seemed permanent at Grey’s Anatomy season 21, episode 18’s beginning, Ben had yet to meet Teddy or the board about his residency status, meaning the chaotic day at Grey Sloan Memorial briefly stopped Ben from being sacked as a resident. It’s unclear whether by the time Ben met Miranda outside the hospital, his trial had ended negatively already, making it necessary for Grey’s Anatomy season 22 to clear up the status of Ben’s residency by the time the medical drama returns.
2Did Dylan’s Surgery Work?
Dylan Had Yet To Wake Up After Amelia’s Operation Ended Successfully
Amelia’s impossible cases in Grey’s Anatomy season 21 increased the difficulty of her surgeries, as many of those she treated were patients who were turned down by previous neurosurgeons based on how difficult it would have been to operate on them and keep them alive. This was also Dylan’s case in Grey’s Anatomy season 21, episode 16, but Amelia still operated on her, only for her condition to worsen exponentially in season 21, episode 17.
With the surgery being done only because Jenna threatened Amelia, it could be just as likely that Dylan’s condition didn’t improve despite the successful surgery.
Jenna’s exasperation thinking the doctors weren’t doing anything to save Dylan as she suffered from locked-in syndrome prompted her to force Amelia’s hand by taking Simone hostage in Grey’s Anatomy season 21, episode 18. However, while Dylan’s surgery was deemed a success by Amelia, Dylan was still unconscious at the episode’s end. With the surgery being done only because Jenna threatened Amelia, it could be just as likely that Dylan’s condition didn’t improve despite the successful surgery. Grey’s Anatomy season 22 will need to clear up the heartbreaking storyline.
1How Will Owen React After Teddy Put Herself First?
Owen Didn’t Have Time To Say What He Felt After Teddy’s Confession
Grey’s Anatomy season 21 is streaming in its entirety on Hulu.
While their talk in Grey’s Anatomy season 21, episode 18’s ending let Owen propose not talking to Nora anymore and choosing their family and his best friend, Teddy, along with his reaction to her words by asking whether Teddy was giving up on them, the full extent of what Teddy’s choice caused in Owen is unknown. Grey’s Anatomy season 22 will have to explain what Teddy and Owen will try after their exchange, as the only thing season 21’s finale explained for now is Teddy’s realization of how much her relationship with Owen hurt her.